Fixed: the free-baseline fit failed whenever the baseline or the signal per unit of complex was larger than 60 signal units, which is the case for raw fluorescence counts and for polarization in mP. Such data came back with a meaningless Kd and a low R², and could wrongly raise the “Kd not identifiable” warning. The fixed-baseline fit was affected only when the signal per unit of complex exceeded 60.
Fits of data on a small numeric scale are unchanged. If you fitted large-valued data with an earlier version, re-run it.
v0.23
22 Aug 2026
English / Chinese interface switch.
2 Sept 2026: a warning when the fitted Kd is below 1% of the fixed concentration. There the data sit in the stoichiometric-titration regime and only an upper bound on Kd can be stated.
1 Oct 2026: when opened from the AptaPilot portal or Launcher, the tool starts in the platform's interface language.
v0.22
26 May 2026
First public release: quadratic binding model, free- and fixed-baseline fits side by side, paste from Excel, replicate-based error bars, CSV and image export.
English / Chinese interface, following the language set on the AptaPilot platform.
v0.9.5
31 Aug 2026
Security release for updates: update metadata is signature-verified (Ed25519) on your machine before anything is applied, and the updater can only write inside the application folder.
v0.9.4
14 June 2026
Maintenance release.
v0.9.3
9 June 2026
First downloadable preview build. The tool page went public on 27 May 2026.